Artvigil 150mg Tablets

What is Artvigil 150mg?

Artvigil 150mg contains Armodafinil, a wakefulness promoting drug used for the treatment of excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea and shift work sleep disorder. It works to stay awake by inhibiting the dopamine transporter (DAT), which decreases the reuptake of dopamine into presynaptic neurons. This increases the amount of dopamine available in the synaptic cleft, which enhances wakefulness and alertness. Armodafinil is the R-enantiomer of modafinil. It is long lasting & more effective than Modafinil. This medication start showing its effect within an hour and it can be lasts for about 12 to 15 hour.

Artvigil 150mg (Armodafinil 150mg) tablet enhances wakefulness and alertness in adult patients with excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea & shift work sleep disorder. It works by modulating various neurotransmitters, particularly dopamine, orexin, norepinephrine, and histamine.

What are The Uses of Artvigil 150mg Tablets?

Artvigil 150 mg is a prescription medication contains Armodafinil as an active constituent used to help people with excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea and shift work sleep disorder.

• Narcolepsy

Patients with narcolepsy, a neurological disease marked by the brain’s inability to control sleep-wake cycles appropriately, are taken Artvigil 150 mg to help manage excessive daytime sleepiness. Artvigil helps people with narcolepsy stay awake and focused during the day by encouraging wakefulness, which enhances their capacity to execute everyday tasks.

• Obstructive sleep apnea (OSA)

When treating patients with obstructive sleep apnea (OSA), such as those receiving continuous positive airway pressure (CPAP) therapy, Artvigil 150 mg is utilized as an additional therapy to lessen residual excessive drowsiness. OSA is a condition where breathing obstructions and poor sleep quality occur due to blockages in the airway during sleep. These patients’ quality of life is enhanced when they are able to stay up during the day, thanks to Artvigil.

• Shift Work Sleep disease (SWSD)

Artvigil 150mg can help people with SWSD, a disease that happens when they work odd hours like night shifts or rotating shifts, to deal with their excessive sleepiness. These unpredictable work hours could mess up the body’s natural circadian rhythm, which would make it hard to sleep at night and stay awake during the day. With the help of Artvigil, these people do their jobs better and stay awake during their shifts.

What are The Dosage Guidelines for Artvigil 150mg Tablets?

• Standard Dosage

The normal dose of 150mg Artvigil is one tablet taken once a day, normally in the morning for ailments like narcolepsy and obstructive sleep apnea.

• Timing for Shift Work Sleep Disorder

For SWSD, Artvigil 150mg ought to be consumed about 1 hour prior to beginning the work shift periods in order to have maximum periods of alertness while on duty.

• Adjustments

Dosage alterations might be needed based on personal reaction and tolerability, especially for those affected by liver malfunction or older individuals.

How to Take Artvigil 150mg Tablet?

Oral Administration:

You should take the tablet with water orally. You may take it along with or without food; however, taking it along with food may delay its effects.

Consistent Timing:

For stable blood levels of the medication, it is advisable that Artvigil be taken at the same time every day.

Avoid Late Dosing:

Avoid taking Artvigil late in the day since it can interfere with nighttime sleep and bring about insomnia.

Missed Dosage Guidelines:

Skip the missed dose:

If you remember about your dose when it is almost time for the next one, just avoid it, leaving other doses as per the rules of administration.

Avoid double dosing:

Do not try to take the drug again in order to cover for another missed one because doing so can lead to increased chances of experiencing reactions.

Medical Consultation:

If there is a tendency to forget medications, speak with the doctor about other methods that can be employed, such as reminders and different modes of administering medication.

Overdosage Guidelines:

Overdose Symptoms:

Severe insomnia, agitation, restlessness, confusion or an increased heart rate may follow an overdose with Artvigil.

First Aid:

In case of an overdose, it is important to go to the hospital right away or ask for help from a poison center on how to manage an overdose.

Guidelines for Supportive Care:

Usually, treatment requires supportive care only without any other type of intervention, close monitoring of cardiovascular and neurological status, and symptom management as needed.

How does An Artvigil 150mg Tablet Work?

Artvigil 150mg is used to promote wakefulness in adult patients with excessive daytime sleepiness caused by narcolepsy, obstructive sleep apnea and shift work sleep disorder. The complex interaction of neurotransmitter pathways is the pharmacological mechanism of the wakefulness-promoting drug armodafinil. Armodafinil’s principal mode of action involves inhibition of dopamine reuptake, which specifically inhibits the brain’s dopamine transporter to raise extracellular dopamine levels. Dopaminergic neurotransmission, which is essential for encouraging alertness and enhancing cognitive function, is improved by this increase in dopamine levels.

Armodafinil not only affects dopamine levels but also the hypocretin (orexin) system, which is crucial for controlling the sleep-wake cycle. Armodafinil helps in maintaining alertness and lessens daytime sleepiness by modifying hypocretin neurons. Additionally, the medication may indirectly activate adrenergic pathways by promoting norepinephrine release, which results in heightened concentration and alertness.

The pharmacological profile of armodafinil also includes increased glutamatergic activity, which may help to improve cognitive abilities, including memory and attention. The excitatory neurotransmitter glutamate is implicated in cognitive functions, and the drug’s therapeutic effects may be attributed to its enhanced release.

Along with better wakefulness, better cognitive function, and less excessive daytime sleepiness, these methods have many benefits. Research suggests that armodafinil’s therapeutic benefits come from the way it affects neurotransmitter systems that control cognitive function and wakefulness. However, the exact ways it works are still unknown.

What are The Side Effects of Artvigil 150mg Tablets?

Headaches, dizziness, nausea, insomnia, dry mouth, stomach upset (nausea and vomiting), anxiety and rash (mostly as a result of allergic reaction) are some of the side effects that have been associated with Artvigil 150mg tablets. Nervousness, tremulousness, and heart palpitations are some of the other symptoms reported; but in rare cases skin problems or mental illnesses may occur.

Precautions & Warnings

• Heart Health

Take precautions with people who have had heart problems in the past, like high blood pressure, coronary artery disease, or arrhythmias, because Armodafinil may make their heart rate and blood pressure go up.

If you have a history of psychiatric problems like bipolar disorder or psychosis, you should be very careful when taking Armodafinil because it may make your symptoms worse or cause mania.

• Liver Impairment

Patients with liver impairment may need to change their dose because their body processes drugs differently and they are more likely to have side effects.

• Renal Function

Individuals who have serious renal impairment should be closely watched because it can affect how quickly drugs are cleared from the body.

• Drug Interactions

You should be aware that Armodafinil may not work as well with some drugs, like oral contraceptives and drugs that are broken down by the liver.

• During pregnancy and breastfeeding

Artvigil has not been proven safe during these times; it should only be used if the possible benefits are greater than the risks.

• Allergic Reactions

Keep an eye out for serious allergic reactions like rashes, swelling, or trouble breathing, and stop using the product if these happen.

• Long-Term Use

Sometimes, people who take Artvigil for a long time might have to reconsider the benefits and risks of their treatment.

Interaction

• CYP450 Enzyme Inhibitors

Taking Armodafinil with CYP450 enzyme inhibitors (like ketoconazole or erythromycin) may raise the amount of drug in your body, which could make its benefits and side effects stronger. It may be necessary to change the dose.

• CYP450 Enzyme Inducers

Taking Armodafinil at the same time as CYP450 enzyme inducers (like rifampin or carbamazepine) can lower its levels, which could make it less effective. It may be necessary to keep an eye on things and change the dose.

• Oral contraception

Because it causes enzymes to be released, armodafinil may make hormonal contraception less effective. Different or extra means of birth control should be thought about.

• Anticoagulants

Armodafinil may change how anticoagulants (like warfarin) are broken down, so INR levels need to be checked regularly to make sure the treatment works.

• Antidepressants

Taking Armodafinil with some types of antidepressants (SSRIs, SNRIs, etc.) may make you more likely to get serotonin syndrome. Check for signs and make changes to the treatment as needed.

• Antiepileptics

Taking this medicine with some others, like phenytoin, may change the amount of the drug in your blood, which can make it harder to control your seizures and mean you need to change your dose.

• Antihypertensives

Armodafinil may make the effects of hypertension drugs worse, which could cause blood pressure to rise. It is suggested that blood pressure be checked often.

This is not a complete list. Doctors and nurses should be careful when mixing Artvigil with other drugs and keep an eye on their patients for possible reactions.

FAQs:

Q. Is Artvigil 150mg safe for elderly patients?

Due to changes in metabolism and a higher sensitivity to the drug, older patients may need to have their doses changed. Your healthcare provider can provide you the right advice.

Q. Can Artvigil 150mg be used during pregnancy?

It has not been proven that taking 150 mg of Artvigil while pregnant is safe. It should only be used if the pros are greater than the cons.

Q. Can I consume alcohol while taking Artvigil 150mg?

It is best to stay away from alcohol because it can raise the risk of side effects and make the medicine less effective.

Q. Can Artvigil 150mg be used for ADHD?

Artvigil 150mg is not FDA-approved for ADHD, but it can be used off-label to improve cognitive function and attention with the help of a healthcare provider.

Q. Can Artvigil 150mg cause allergic reactions?

Yes, some allergic reactions that could happen are rashes, itching, swelling, or trouble breathing. Seek medical attention if these occur.